A new algorithm leverages both topologicaland biological information to predict protein-protein interactions . It has competitive or higher accuracy on biologically validated test sets . It can effectively predict the entire humaninteractome compared with methods that leverage only one source of biologicalinformation . The results show that topological plussequence-based computational methods can effectively . They can . effectively predict . the entire . humaninteractionome compared to methods that leverages only one biological information, such as that of topological and sequence-based approaches on PPIs datasets, showing . that they have competitive or . higher accuracy .

Author(s) : Luca Becchetti, Adriano Fazzone, Leonardo Martini

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Keywords : protein - effectively - based - methods - predict -

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